Inspire Pharmaceuticals, Inc. - Publications & Presentations for 1996 through 1999

Posters, Presentations & Publications
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2008 2007 2006 2005 2004 2003 2002 2001 2000 1996-1999

Sabater JR, Mao YM, Shaffer C, James MK, O'Riordan TG, Abraham WM. Aerosolization of P2Y2-receptor agonists enhances mucociliary clearance in sheep. J Appl Physiol, 1999 Dec, 87(6):2191-2196.

Johnson FL, Zeman KL, Foy CE, Shaffer CL, Bennett WD. Aerosolized UTP stimulates mucociliary clearance in smokers with mild chronic bronchitis. J Aerosol Med, 1999 Summer, 12(2):141.

Yerxa BR, Elena PP, Caillaud T, Amar T, Evans R. INS365, A P2Y2 receptor agonist, increases Schirmer scores in albino rabbits. Poster presented at The Association for Research in Vision and Ophthalmology (ARVO) 1999 Annual Meeting. 1999 May 9-14; Ft. Lauderdale, Florida, USA.

Yerxa BR, Johnson FL. P2Y2 receptor agonists: structure, activity and therapeutic utility. Drugs of the Future, 1999, 24(7):759-769.

Dougherty RW, Croom D, James M, Jones C, Pendergast W, Yerxa B, Abraham W, Sabater J, Davis CW, Stutts MJ. Effects of INS365, a P2Y2 receptor agonist, on components of the mucociliary clearance system. Poster presented at the North American Cystic Fibrosis Conference. 1998 October 15-18; Montreal, Quebec, Canada.

Shaffer C, Jacobus K, Yerxa B, Johnson F, Griffin W, Evans R, Edgar P. INS365, a novel P2Y2 receptor agonist and ion channel modulator for the treatment of cystic fibrosis: results from initial phase I study. Poster presented at the North American Cystic Fibrosis Conference. 1998 October 15-18; Montreal, Quebec, Canada.

Siddiqi SM, Shaver SR, Pendergast W, Yerxa BR, Croom DK, Dougherty RW, James MK, Jones AC, and Rideout JL. Molecular modeling of the P2Y2 purinoceptor and synthesis of selected ligands. Poster presented at the 6th International Symposium on Adenosine and Adenine Nucleotides. 1998 May 19-24; Ferrara, Italy.

Shaffer C, Jacobus K, Foy C, Pue C, Donohue J, Bennett W, Ye H, Graham C, Noone P, and Drutz D. Controlled clinical studies indicate that INS316 (Uridine 5'-triphosphate) a P2Y2 receptor agonist stimulates mucociliary clearance and enhances sputum expectoration. Poster presented at the American Thoracic Society International Conference. 1998 April 24-29; Chicago, Illinois, USA.

Shaffer C, Jacobus K, Foy C, Pue C, Donohue J, Bennett W, Ye H, Graham C, Noone P, and Drutz D. Controlled clinical studies indicate that INS316 (Uridine 5'-triphosphate) a P2Y2 receptor agonist stimulates mucociliary clearance and enhances sputum expectoration. Am J Respir Crit Care Med, 1998, 157(3):A796.

Shaver SR, Pendergast W, Siddiqi SM, Yerxa BR, Croom DK, Dougherty RW, James MK, Jones AN, and Rideout JL. 4-substituted uridine 5'-triphosphates as agonists of the P2Y2 purinergic receptor. Nucleosides & Nucleotides, 1997, 16(7-9):1099-1102.

Shaver SR, Pendergast W, Siddiqi SM, Yerxa BR, Croom DK, Dougherty RW, James MK, Jones AN, Rideout JL. 4-Substituted uridine 5'-triphosphates as agonists of the P2Y2 purinergic receptor. Poster presented at the Twelfth International Roundtable of Nucleosides, Nucleotides, and Their Biological Applications. 1996 September 15-19; La Jolla, California, USA.

Drutz D, Shaffer C, LaCroix K, Jacobus K, Knowles M, Bennett W, Regnis J, Hohneker K, Noone P, Davis W, Geary C, and Boucher R. Uridine 5'-Triphosphate (UTP) regulates mucociliary clearance via purinergic receptor activation. Poster presented at the Purines '96. Molecular, Pharmacological and Therapeutic Advances. 1996 July 6-9; Milan, Italy.

Pendergast W, Siddiqi SM, Rideout JL, James MK, and Dougherty RW. Stabilized uridine triphosphate analogs as agonists of the P2Y2 purinergic receptor. Poster presented at the Purines '96. Molecular, Pharmacological and Therapeutic Advances. 1996 July 6-9; Milan, Italy.

Drutz D, Shaffer C, LaCroix K, Jacobus K, Knowles M, Bennett W, Regnis J, Hohneker K, Noone P, Davis W, Geary C, and Boucher R. Uridine 5'-triphosphate (UTP) regulates mucociliary clearance via purinergic receptor activation. Drug Devel Res, 1996, 37:185.

Pendergast W, Siddiqi SM, Rideout JL, James MK, and Dougherty RW. Stabilized uridine triphosphate analogs as agonists of the P2Y2 purinergic receptor. Drug Devel Res, 1996, 37:133.

James MK and Shaffer CL. Pharmacologic approaches to correct the bioelectric deficits in cystic fibrosis. Expert Opinion on Investigational Drugs, 1996, 5(9):1163-1171.

Page last updated: 20-Jun-2008

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