Posters, Presentations & Publications
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2008  2007  2006  2005  2004  2003  2002  2001  2000  1996-1999

Kellerman D, Evans R, Mathews D, Shaffer C. Inhaled P2Y2 receptor agonists as a treatment for patients with Cystic Fibrosis lung disease. Adv Drug Deliv Rev. 2002 Dec 5;54(11):1463-1474.

Johnson FL, Donohue JF, Shaffer CL. Improved sputum expectoration following a single dose of INS316 in patients with chronic bronchitis. Chest. 2002 Dec;122(6): 2021-2029.

Meltzer EO, Ice JC, LaVange LM, Kellerman DJ, Schaberg AE. INS37217, a P2Y2 receptor agonist given intranasally, is well tolerated and decreases saccharin transport time in subjects with and without perennial allergic rhinitis. Results presented at the 2002 American College of Allergy, Asthma & Immunology Annual Meeting. 2002 November 15-20, San Antonio, Texas.

Douglass J, Patel RI, Redick C, Brubaker K, Jones AC, Shaver SR, Yerxa B, Baurand A, Gachet C, Boyer JL. Ribose and nucleobase modifications to nucleotides that confer antagonist properties against the platelet P2Y12 receptor. Poster presented at The Platelet ADP Receptors 2nd International Meeting. 2002 October 3-5; Sardinia, Italy.

Deterding R, Engels J, Shaffer C Kellerman D Mathews D LaVange L, Gorden J, Quittner A, Williams J, Ramsey B. Safety and tolerability of INS37217 inhalation solution, a novel P2Y2 receptor agonist, in patients with mild to moderate cystic fibrosis: Results of a phase 1/2 multi-center study. Poster presented at the 2002 North American Cystic Fibrosis Conference. 2002 October 3-6; New Orleans, Louisiana, USA. Poster in PDF

Deterding R, Engels J, Shaffer C Kellerman D Mathews D LaVange L, Gorden J, Quittner A, Williams J, Ramsey B. Safety and tolerability of INS37217 inhalation solution, a novel P2Y2 receptor agonist, in patients with mild to moderate cystic fibrosis: Results of a phase 1/2 multi-center study. Powerpoint presentation by Robin Deterding, MD at the 2002 North American Cystic Fibrosis Conference. 2002 October 3-6; New Orleans, Louisiana, USA.

Yerxa BR, Sabater JR, Davis CW, Stutts MJ, Lang-Furr M, Picher M, Jones AC, Cowlen M, Dougherty R, Boyer J, Abraham WM, Boucher RC. Pharmacology of INS37217 [P1-(uridine 5')-P4-(2'-deoxycytidine 5')tetraphosphate, Tetrasodium Salt], a next-generation P2Y2 receptor agonist for the treatment of cystic fibrosis. J Pharmacol Exp Ther, 2002 Sep, 302(3):871-880.

Plourde R Jr., Brown EG, Pelaez T, Peral A, Peterson W, Yerxa B, Pintor J. Design of novel melatonin analogs for reduction of intraocular pressure. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Jones AC, Redick CC, Zhang V, Brubaker K, Patel RI, Boyer JL. Characterization of 2MeSADP response in wild type 1321N1 human astrocytoma cells. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Patel RI, Douglass J, Redick C, Brubaker K, Jones AC, Shaver SR, Yerxa B, Boyer JL. Identification of a ribose substitution that confers antagonist properties to ADP against the platelet P2Y12 receptor. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Cowlen MS, Bazemore EK, Gomez LM, Yerxa B, Peterson WM, Stutts MJ. P2Y2 receptor gene expression and regulation of short circuit current (Isc) by P2Y2 receptor agonists in endocervical epithelial cells. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Zhang VZ, Yerxa BR, Cowlen MS. Cellular distribution of P2Y2 receptor gene expression in the primate gastrointestinal tract by in situ hybridization. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Brubaker KE, Redick C, Patel R, Jones A, Boyer JL. High throughput screening for agonists and antagonists of ADP receptors. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Douglass J, Yerxa B, Boyer JL, Redick C, Patel R, Jones A. Dinucleoside tetraphosphates modified with lipophilic substituents on the ribose hydroxyls: selected structure-activity relationships at nucleotide G-protein coupled receptors. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Boyer JL, Patel RI, Redick C, Brubaker K, Douglass J, Shaver S, Baurand A, Gachet C, Yerxa B. Inhibition of platelet aggregation by novel selective P2Y12 receptor antagonists. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Baurand A, Patel RI, Redick K, Douglass J, Shaver S, Yerxa B, Boyer JL, Cazenave JP, Gachet C. Reduced thromboembolism in mice treated with a novel class of P2Y12 receptor antagonists. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Crean C, Douglass J, Yerxa B, Redick K, Patel R, Jones A. Dinucleoside tetraphosphates with base lipophilic substituent modifications: selected structure-activity relationships at nucleotide G-protein coupled receptors. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Gomez L, Venturini AE, Peterson WM. Profiling the activation of many intracellular signaling proteins in response to stimulation of P2Y2 receptors using a high-output western blot assay. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Brown EG, Boyer J, Shaver SR. Detection of INS316, INS365 and other nucleotides in plasma and fluids by LC/MS. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Bednarski K, Douglass JG, Redick CC, Jones AC, Patel RI, Shaver SR. Modified nucleoside polyphosphates as platelet aggregation. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Shaver SR, Douglass JG, Brown EG, Patel RI, Redick CC, Jones AC, Boyer JL, Picher M, Yerxa BR. P2Y receptor agonists: a comparison of mixed-base dinucleotides versus same-base dinucleotides and their deoxyribo-analogues. Poster presented at IUPHAR 2002 - XIVth World Congress of Pharmacology. 2002 July 7-12; San Francisco, California, USA.

Johnson FL, Yung RC-W, Sussman R, ZuWallack RL, Kellerman DJ. Improved lung cancer diagnostic value of sputum induced with a single inhaled dose of INS316 (uridine 5'-triphosphate). Poster presented at the American Thoracic Society (ATS) 98th International Conference. 2002 May 17-22; Atlanta, Georgia, USA.

Peral A, Bautista A, Carracedo G, Yerxa BR, Pintor J. Nucleotides and dinucleotides increase re-epithelialisation in rabbit corneal wounds. Poster presented at The Association for Research in Vision and Ophthalmology (ARVO) 2002 Annual Meeting. 2002 May 5-10; Fort Lauderdale, Florida, USA.

Wen Q, Li Y, Kuang K, Zuniga FA, Iserovich P, Yerxa B, Fischbarg J. Effects of P2Y2 agonists on lipid secretion by cultured rabbit meibocytes. Poster presented at The Association for Research in Vision and Ophthalmology (ARVO) 2002 Annual Meeting. 2002 May 5-10; Fort Lauderdale, Florida, USA.

Donshik PC, Sall KN, Cacioppo LR, Whitsell RN, Mayhew AL, Yerxa BR, Crockett RS, Kellerman DJ. Presenting symptoms from diary cards for dry eye clinical trial subjects. Poster presented at The Association for Research in Vision and Ophthalmology (ARVO) 2002 Annual Meeting. 2002 May 5-10; Fort Lauderdale, Florida, USA.

Kellerman DJ. P2Y2 receptor agonists: a new class of medication targeted at improved mucociliary clearance. Chest. 2002 May;121 (5 Suppl): 201S-205S.

Redick CC, Jones AC, Zhang V, Brubaker K, Patel RI, Boyer JL. Endogenous expression of P2Y1 receptors in 1321N1 human astrocytoma cells. Poster presented at the Federation of American Societies for Experimental Biology Annual Meeting. 2002 April 20-24; New Orleans, Louisiana, USA.

Pintor J, Peral A, Hoyle C, Redick C, Douglass J, Yerxa B. Effects of diadenosine polyphosphates on tear secretion in New Zealand white rabbits. J Pharmacol Exp Ther, 2002 Jan, 300(1):291-297.

Pendergast W and Evans R. P2Y Receptor Agonists: Role in Mucosal Hydration and Mucociliary Clearance. New Drugs for Asthma, Allergy and COPD, 2002, 31(5):165-168.

Yerxa BR, Mundasad M, Sylvester RN, Garden JC, Cooper M, Kellerman DJ. Ocular safety of INS365 ophthalmic solution, a P2Y2 agonist, in patients with mild to moderate dry eye disease. Adv Exp Med Biol. 2002; 506(Pt B): 1251-1257.

Yerxa BR. Industry perspective. Adv Exp Med Biol. 2002;506 (Pt B):1343-1344.

Yerxa BR, Douglass JG, Elena PP, Caillaud T, Amar T, Edick C, Peterson WM. Potency and duration of action of synthetic P2Y2 receptor agonists on Schirmer scores in rabbits. Adv Exp Med Biol. 2002;506 (Pt A): 261-265.

 

Page last updated: 23-Jun-2008
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